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Anti-Factor VIII, Recombinant [RFF-VIII:c/8]

Info

Catalogue Number 153358
Applications IF Fn WB
Antigen/Gene or Protein Targets Factor VIII
Reactivity Human
Relevance The commonest severe congenital bleeding disorder in all races is haemophilia A. The characteristic defect is a lack of coagulation factor VIII:C. Factor VIII:C is a glycoprotein that functions as a cofactor for factor IXa which, in the presence of calcium and phospholipids, converts factor X to the activated form Xa. This antibody binds to human FVIII:C heavy chain and inhibits its function.
Host Mouse
Immunogen Purified human factor VIII
Subclass IgG1 kappa
Formulation PBS
Concentration 1mg/ml
Research Area Cardiovascular
Notes Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References

There are 1 reference entries for this reagent.

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References: 1 entry

Original hybridoma first published in: Rotblat et al. 1983. J Lab Clin Med. 101(5):736-46. PMID: 6403638.


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References: 1 entry

Original hybridoma first published in: Rotblat et al. 1983. J Lab Clin Med. 101(5):736-46. PMID: 6403638.


Add a reference

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