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Anti-CEACAM3/5 (CD66d/e) [308/3-3] monoclonal antibody

Invented by Dr Bernhard B. Singer at LeukoCom

Info

Catalogue Number 153326
Applications ELISA FACS IP WB
Antigen/Gene or Protein Targets CEACAM3/5, CD66d, CD66e
Synonyms CD66d, CD66e
Reactivity Human
Relevance CEACAM3/5 belong to the immunoglobulin superfamily. The proteins contains 1 Ig-like V-type (immunoglobulin-like) domain and the cytosolic domain is involved in S100A9 interaction. Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
Host Mouse
Immunogen Recombinant soluble human CEACAM3-Fc produced in HEK293 cells
Subclass IgG1 kappa
Molecular Weight (kDa) 30, 180
Myeloma Used P3/NS1/1-Ag4.1
Strain Balb/c
Notes Clone 308/3-3 reacts with human CEACAM3 and CEACAM5, but not human CEACAM1/4/6/7/8, rat CEACAM1, or mouse CEACAM1 & CEACAM2.
Research Area Immunology

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