Anti-sCD40 (soluble), Recombinant [T8P2G4*A6]
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (0)
- Inventor Info
Info
| Catalogue Number | 153286 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form) |
| Synonyms | CD40 Molecule; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD40; CD40 Antigen; P50 |
| Reactivity | Human |
| Relevance | CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence) |
| Subclass | IgG1 kappa |
| Formulation | PBS |
| Concentration | 1mgml-1 |
| Positive Control | IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates |
| Research Area | Cancer, Immunology |
| Notes |
Recombinant monoclonal antibody produced from the original monoclonal cell line. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. Five products available based on this clone: - Anti-sCD40 [T8P2G4*A6], Mouse IgG1, Kappa - Anti-sCD40 [T8P2G4*A6], Rabbit IgG, Kappa - Anti-sCD40 [T8P2G4*A6], Human IgG4-S228P, Kappa - Anti-sCD40 [T8P2G4*A6], Human IgG1, Kappa - Anti-sCD40 [T8P2G4*A6], Human IgG1, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors |
References
There are 0 reference entries for this reagent.
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
