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Anti-BORIS, Recombinant [20B11]

Invented by Prof Elena Klenova at Absolute Antibody, University of Essex

Info

Catalogue Number 153257
Applications ChIP ELISA IHC IF IP WB
Antigen/Gene or Protein Targets BORIS
Synonyms Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor (zinc finger protein) like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, Ctcfl, CTCFL_HUMAN, dJ579F20.2, HMG 1L1, HMGB1L1, MGC163358, MGC169105, MGC169106
Reactivity Human
Relevance Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
Host Mouse
Immunogen Synthetic peptide within the BORIS C-terminal domain (aa 614-648) (CG)GEMFPVACRETTARVKEE (NB - the first two aa do not belong to BORIS)
Subclass IgG3 kappa
Formulation PBS
Concentration 1mgml-1
Positive Control MCF7 cell lysates
Research Area Cancer, Epigenetics & Nuclear Signalling
Notes Recombinant monoclonal antibody produced from the original monoclonal cell line. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

Five products based on this clone:
- Anti-BORIS [20B11], Mouse IgG3, Kappa
- Anti-BORIS [20B11], Rabbit IgG, Kappa
- Anti-BORIS [20B11], Human IgG1, Kappa
- Anti-BORIS [20B11], Human IgG1, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors
- Anti-BORIS [20B11], Human IgG4-S228P, Kappa

References

There are 1 reference entries for this reagent.

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References: 1 entry

Debruyne et al. 2019. Nature. 572(7771):676-680. PMID: 31391581.


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References: 1 entry

Debruyne et al. 2019. Nature. 572(7771):676-680. PMID: 31391581.


Add a reference