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Anti-CD8, Recombinant [14]

Info

Catalogue Number 153256
Applications ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets CD8
Synonyms Leu2
Reactivity Human
Relevance CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. Clone 14 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of CD4/CD8 ratios in immune deficiencies, rheumatoid arthritis and multiple sclerosis.
Host Mouse
Immunogen Fibronectin-purified human monocytes
Subclass IgG1
Formulation PBS
Concentration 1mgml-1
Research Area Immunology
Notes Recombinant monoclonal antibody produced from the original monoclonal cell line. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

Five products based on this clone:
- Anti-CD8 [14], Mouse IgG1, Kappa
- Anti-CD8 [14], Rabbit IgG, Kappa
- Anti-CD8 [14], Human IgG1, Kappa
- Anti-CD8 [14], Human IgG1, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors
- Anti-CD8 [14], Human IgG4-S228P, Kappa

References

There are 1 reference entries for this reagent.

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References: 1 entry

Original hybridoma first published in: Hogg et al. 1999. J Clin Invest. 103(1):97-106. PMID: 9884339.


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References: 1 entry

Original hybridoma first published in: Hogg et al. 1999. J Clin Invest. 103(1):97-106. PMID: 9884339.


Add a reference