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Anti-CD18 [BU86]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153230
Applications FACS IHC
Antigen/Gene or Protein Targets CD18
Synonyms Cell differentiation 18; Integrin beta-2; ITGB2 gene
Reactivity Human
Relevance The CD18 protein is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of alpha and beta chains. A given chain may combine with multiple partners resulting in different integrins. In humans a lack of CD18 causes leukocyte adhesion deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues. The beta 2 integrins have also been found in a soluble form and these ligand binding proteins are inversely associated with disease activity in the autoimmune disease spondyloarthritis.
Host Mouse
Subclass IgG1
Strain Balb/c
Research Area Adhesion, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

References

There are 1 reference entries for this reagent.

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References: 1 entry

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.


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References: 1 entry

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.


Add a reference