Anti-CD55 [BU84]
Invented by Dr Margaret Goodall from University Of Birmingham
Invented at University Of Birmingham
- Datasheet
- References (5)
- Inventor Info
Info
| Catalogue Number | 153228 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | CD97 Ligand |
| Synonyms | Complement decay-accelerating factor 55; Dcay accelerating factor for complement; DAF |
| Reactivity | Human |
| Relevance |
CD55 regulates the complement system on the cell surface. It recognizes C4b and C3b fragments that are created during classical complement pathway and alternative complement pathway activation and indirectly blocks the formation of the membrane attack complex. CD97 is a member of the epidermal growth factor-seven transmembrane family. It affects tumour aggressiveness by binding its cellular ligand CD55 and exhibits adhesive properties. Previous studies have shown that CD97 and CD55 are involved in the dedifferentiation, migration, invasiveness and metastasis of tumours. |
| Host | Mouse |
| Immunogen | Pre-B cells |
| Subclass | IgG2a |
| Strain | Balb/c |
| Research Area | Adhesion, Cancer, Cell Type or Organelle Marker, Immunology |
References: 5 entries
Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.
Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.
Origin and properties of soluble CD21 (CR2) in human blood.
Europe PMC ID: 9737663
Buescher et al. 1991. Public Health Rep. 106(3):333-8. PMID: 1905057.
Problems in estimating the number of women in need of subsidized prenatal care.
Europe PMC ID: 1905057
Add a reference
References: 5 entries
Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.
Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.
Origin and properties of soluble CD21 (CR2) in human blood.
Buescher et al. 1991. Public Health Rep. 106(3):333-8. PMID: 1905057.
Problems in estimating the number of women in need of subsidized prenatal care.
Add a reference
