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Anti-Germinal Centre macrophages [BU83]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153227
Applications IHC
Antigen/Gene or Protein Targets Macrophages
Synonyms PB33
Reactivity Human
Relevance Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
Host Mouse
Immunogen Pre-B cells
Subclass IgG2a
Strain Balb/c
Research Area Immunology

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