Anti-CD45RA [BU82]
Invented by Dr Margaret Goodall from University Of Birmingham
Invented at University Of Birmingham
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Info
| Catalogue Number | 153226 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | CD45RA |
| Synonyms | Protein tyrosine phosphatase receptor type C; PTPRC; |
| Reactivity | Human |
| Relevance | CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells. |
| Host | Mouse |
| Immunogen | Germinal centre B cells |
| Subclass | IgG2a |
| Strain | Balb/c |
| Research Area | Cell Type or Organelle Marker, Immunology, Stem Cell Biology |
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