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Anti-CD45RA [BU82]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153226
Applications IHC
Antigen/Gene or Protein Targets CD45RA
Synonyms Protein tyrosine phosphatase receptor type C; PTPRC;
Reactivity Human
Relevance CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells.
Host Mouse
Immunogen Germinal centre B cells
Subclass IgG2a
Strain Balb/c
Research Area Cell Type or Organelle Marker, Immunology, Stem Cell Biology

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