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Anti-CD21 [BU80]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153223
Applications IHC
Antigen/Gene or Protein Targets CD21
Synonyms Complement receptor type 2; CR2; complement C3d receptor, C3DR, Epstein-Barr virus receptor
Reactivity Human
Relevance Cluster of differentiation 21 (CD21) is a protein encoded by the CR2 gene in humans. It is involved in the complement system and binds to iC3b (an inactive derivative of C3b). B cells are known to have CR2 receptors on their surfaces allowing the complement system to act in B-cell maturation and activation.
Genetic variations are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) which is a chronic autoimmune disease with an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes.
Host Mouse
Immunogen Daudi cell line (B lymphoblast)
Subclass IgG1
Strain Balb/c
Research Area Immunology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.


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References: 3 entries

Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.


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