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Anti-CD44 [BU75]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153222
Applications FACS IHC IF IP WB
Antigen/Gene or Protein Targets CD44
Synonyms HCAM; homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; Hermes antigen; lymphocyte homing receptor; ECM-III; HUTCH-1.
Reactivity Human
Relevance The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes.
Host Mouse
Immunogen Folicual dentritic cells and germinal centre B cells
Positive Control Human tonsil tissue, HL-60 whole cell lysate, HeLa whole cell lysate
Subclass IgG2a
Strain Balb/c
Research Area Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.


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References: 3 entries

Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.


Add a reference