Anti-CD44 [BU75]
Invented by Dr Margaret Goodall from University Of Birmingham
Invented at University Of Birmingham
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 153222 |
| Applications | FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | CD44 |
| Synonyms | HCAM; homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; Hermes antigen; lymphocyte homing receptor; ECM-III; HUTCH-1. |
| Reactivity | Human |
| Relevance | The CD44 antigen is a cell-surface glycoprotein involved in cell to cell and cell-matrix interactions, cell adhesion and migration, which it achieves through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. |
| Host | Mouse |
| Immunogen | Folicual dentritic cells and germinal centre B cells |
| Positive Control | Human tonsil tissue, HL-60 whole cell lysate, HeLa whole cell lysate |
| Subclass | IgG2a |
| Strain | Balb/c |
| Research Area | Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology |
References: 3 entries
Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.
Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.
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References: 3 entries
Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.
Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
Leucocyte Typing VII, (2002): edited by D.Y. Mason, OUP, Oxford.
Add a reference
