Cancer Research Technology
Log in Register
Menu

Anti-CD21 [BU35]

Invented by Dr Margaret Goodall at University Of Birmingham

Info

Catalogue Number 153217
Applications FACS IHC IF IP
Antigen/Gene or Protein Targets CD21
Synonyms Complement receptor type 2; CR2; complement C3d receptor, C3DR, Epstein-Barr virus receptor
Reactivity Human
Relevance Cluster of differentiation 21 (CD21) is a protein encoded by the CR2 gene in humans. It is involved in the complement system and binds to iC3b (an inactive derivative of C3b). B cells are known to have CR2 receptors on their surfaces allowing the complement system to act in B-cell maturation and activation.
Genetic variations are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) which is a chronic autoimmune disease with an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes.
Host Mouse
Immunogen B lymphoblastoid cell line: HFB1
Subclass IgG2b
Strain Balb/c
Research Area Immunology

References

There are 10 reference entries for this reagent.

View All References

References: 10 entries

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.

Masilamani et al. 2002. J Immunol Methods. 270(1):11-8. PMID: 12379334.

Purification and characterization of soluble CD21 from human plasma by affinity chromatography and density gradient centrifugation.

Europe PMC ID: 12379334

Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.

Origin and properties of soluble CD21 (CR2) in human blood.

Europe PMC ID: 9737663

Ling et al. 1992. Immunobiology. 185(2-4):403-14. PMID: 1280620.

Properties of soluble CR2 in human serum.

Europe PMC ID: 1280620

Buescher et al. 1991. Public Health Rep. 106(3):333-8. PMID: 1905057.

Problems in estimating the number of women in need of subsidized prenatal care.

Europe PMC ID: 1905057


Add a reference

References: 10 entries

Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.

Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.

Masilamani et al. 2002. J Immunol Methods. 270(1):11-8. PMID: 12379334.

Purification and characterization of soluble CD21 from human plasma by affinity chromatography and density gradient centrifugation.

Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.

Origin and properties of soluble CD21 (CR2) in human blood.

Ling et al. 1992. Immunobiology. 185(2-4):403-14. PMID: 1280620.

Properties of soluble CR2 in human serum.

Buescher et al. 1991. Public Health Rep. 106(3):333-8. PMID: 1905057.

Problems in estimating the number of women in need of subsidized prenatal care.


Add a reference