Anti-MHC II [BU27]
Invented by Dr Margaret Goodall from University Of Birmingham
Invented at University Of Birmingham
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 153216 |
| Applications | FACS IHC WB |
| Antigen/Gene or Protein Targets | MHC II (P, Q, R) |
| Synonyms | Major histocompatibility complex II; HLA class II histocompatibility antigen; Human leukocyte antigen; |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). |
| Host | Mouse |
| Immunogen | Waldenstrom's Macroglobulinaemia |
| Subclass | IgG1 |
| Strain | Balb/c |
| Notes | Reacts only with MHC class II a and b dimers, does not react with either free MHC II a or b chains |
| Research Area | Immunology |
References: 4 entries
Bosshart et al. 1998. Blood. 92(7):2252-9. PMID: 9746762.
Deficient major histocompatibility complex class II antigen presentation in a subset of Hodgkin's disease tumor cells.
Europe PMC ID: 9746762
Fondaneche et al. 1998. Hum Mol Genet. 7(5):879-85. PMID: 9536093.
Genetic and molecular definition of complementation group D in MHC class II deficiency.
Europe PMC ID: 9536093
Add a reference
References: 4 entries
Bosshart et al. 1998. Blood. 92(7):2252-9. PMID: 9746762.
Deficient major histocompatibility complex class II antigen presentation in a subset of Hodgkin's disease tumor cells.
Fondaneche et al. 1998. Hum Mol Genet. 7(5):879-85. PMID: 9536093.
Genetic and molecular definition of complementation group D in MHC class II deficiency.
Add a reference
