Anti-XPF [4H4]
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153204 |
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | XPF |
| Synonyms | DNA excision repair protein ERCC-4, DNA repair protein complementing XP-F cells, Xeroderma pigmentosum group F-complementing protein |
| Reactivity | Human |
| Relevance | Nucleotide excision repair (NER) is a DNA repair pathway that removes lesions induced by a variety of agents such as UV irradiation. ERCC1 and XPF form the heterodimer ERCC1-XPF, forming a DNA endonuclease that is essential for the dual incision step of NER (cleaves 5' of the DNA lesion). |
| Host | Mouse |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM 5% FCS |
| Strain | Balb/c |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 2 entries
Bhagwat et al. 2009. Cancer Res. 69(17):6831-8. PMID: 19723666.
IF WB
Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue.
Europe PMC ID: 19723666
Add a reference
References: 2 entries
Bhagwat et al. 2009. Cancer Res. 69(17):6831-8. PMID: 19723666.
IF WB
Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue.
Add a reference
