Cancer Research Technology
Log in Register
Menu

Anti-XPF [4H4]

Info

Catalogue Number 153204
Applications ELISA IF WB
Antigen/Gene or Protein Targets XPF
Synonyms DNA excision repair protein ERCC-4, DNA repair protein complementing XP-F cells, Xeroderma pigmentosum group F-complementing protein
Reactivity Human
Relevance Nucleotide excision repair (NER) is a DNA repair pathway that removes lesions induced by a variety of agents such as UV irradiation. ERCC1 and XPF form the heterodimer ERCC1-XPF, forming a DNA endonuclease that is essential for the dual incision step of NER (cleaves 5' of the DNA lesion).
Host Mouse
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM 5% FCS
Strain Balb/c
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Bhagwat et al. 2009. Cancer Res. 69(17):6831-8. PMID: 19723666.

IF WB

Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue.

Europe PMC ID: 19723666


Add a reference

References: 2 entries

Bhagwat et al. 2009. Cancer Res. 69(17):6831-8. PMID: 19723666.

IF WB

Immunodetection of DNA repair endonuclease ERCC1-XPF in human tissue.


Add a reference

Inventor Information