Anti-S100A8, Polyclonal [NH2]
Invented by Prof Nancy Hogg from Cancer Research UK London Research Institute: Lincoln's Inn Fields
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153161 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | S100A8 |
| Synonyms | MRP-8, calgranulin A |
| Reactivity | Human |
| Relevance | S100A8, together with heterodimeric partner S100A9, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours. |
| Host | Rabbit |
| Immunogen | Recombinant human S100A8 (MRP-8) |
| Formulation | Whole serum |
| Molecular Weight (kDa) | 8 |
| Notes |
Western blotting, 1:10,000; Immunoprecipitation, 2-3 ug; Immunohistology, 1:1000 Application dilutions are based on using crude serum. Staining pattern (sub-cellular localisation of antibody): cytosolic protein (with partner S100A9 constitutes 45% protein in neutrophils; 1% in monocytes; also secretory epithelium). |
| Positive Control | Human neutrophils |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology, Neurobiology |
References: 2 entries
Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813.
A comparison of human S100A12 with MRP-14 (S100A9).
Europe PMC ID: 10973813
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References: 2 entries
Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813.
A comparison of human S100A12 with MRP-14 (S100A9).
Add a reference
