Cancer Research Technology
Log in Register
Menu

Villin-Cre Apcfl/+ KRasG12D/+ Mouse

Info

Catalogue Number 152932
Antigen/Gene or Protein Targets KRasG12D
Disease Keywords Colorectal cancer
Synonyms GTPase KRas
K-Ras 2
Ki-Ras
c-K-ras
c-Ki-ras
Model Mutant
Relevance Oncogenic mutations in the K-ras gene occur in 50% of human colorectal cancers. However, the precise role that K-ras oncogenes play in tumor formation is still unclear. To address this issue, we have conditionally expressed an oncogenic K-rasD12 allele in the small intestine of adult mice either alone or in the context of Apc deficiency.
Conditional Yes
Research Area Cancer, Genetic Studies Tools

References

There are 0 reference entries for this reagent.

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor