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Anti-XPA [2A4]

Info

Catalogue Number 152930
Applications IHC IF WB
Antigen/Gene or Protein Targets XPA
Synonyms DNA repair protein complementing XP A cells, DNA repair protein complementing XP-A cells, DNA repair protein complementing XPA cells, Excision repair controlling, Xeroderma pigmentosum 1, Xeroderma pigmentosum complementation group A, Xeroderma pigmentosum group A complementing protein, Xeroderma pigmentosum group A-complementing protein, XP 1, XP1, xpa, Xpac
Reactivity Human
Relevance XPA binds to the Replication Protein A (RPA) and is a core component of the nucleotide excision repair pathway. XPA is involved in one of the complementation groups of the heritable condition Xeroderma pigmentosum, where defects in nucleotide excision repair result in increased susceptibility to mutagens including UV.
Host Mouse
Immunogen His-tagged recombinant human XPA protein.
Positive Control HeLa cell lysate
Subclass IgG1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes 2A4 may be used for the nuclear staining of XPA in human cells.
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References

There are 2 reference entries for this reagent.

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References: 2 entries

HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.

Europe PMC ID: 23209410

O'Dowd et al. 2012. PLoS Pathog. 8(11):e1003038. PMID: 23209410.

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References: 2 entries

HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.

O'Dowd et al. 2012. PLoS Pathog. 8(11):e1003038. PMID: 23209410.

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Inventor Information