Anti-RAD53 [EL7-E1]
Invented at IFOM-IEO
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | WB |
| Antigen/Gene or Protein Targets | RAD53 |
| Synonyms | Checkpoint Kinase 2; CHK2 Checkpoint Homolog; Cds1 Homolog; HuCds1; RAD53; HCds1; CDS1; CHK2; Checkpoint-Like Protein CHK2; PP1425; LFS2 |
| Reactivity | Saccharomyces cerevisiae |
| Relevance | RAD53 is a serine/threonine-protein kinase that controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. RAD53 phosphorylates proteins on serine, threonine, and tyrosine amino acids. It prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. RAD53 seems to be involved in the phosphorylation of histone demethylase RPH1. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 2 entries
Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.
Characterization of the activation domain of the Rad53 checkpoint kinase.
Europe PMC ID: 18287812
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References: 2 entries
Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.
Characterization of the activation domain of the Rad53 checkpoint kinase.
Add a reference
