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Anti-RAD53 [EL7-E1]

Info

Applications WB
Antigen/Gene or Protein Targets RAD53
Synonyms Checkpoint Kinase 2; CHK2 Checkpoint Homolog; Cds1 Homolog; HuCds1; RAD53; HCds1; CDS1; CHK2; Checkpoint-Like Protein CHK2; PP1425; LFS2
Reactivity Saccharomyces cerevisiae
Relevance RAD53 is a serine/threonine-protein kinase that controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. RAD53 phosphorylates proteins on serine, threonine, and tyrosine amino acids. It prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. RAD53 seems to be involved in the phosphorylation of histone demethylase RPH1.
Host Mouse
Myeloma Used Sp2/0
Research Area Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

References

There are 2 reference entries for this reagent.

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References: 2 entries

Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.

Characterization of the activation domain of the Rad53 checkpoint kinase.

Europe PMC ID: 18287812


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References: 2 entries

Fiorani et al. 2008. Cell Cycle. 7(4):493-9. PMID: 18287812.

Characterization of the activation domain of the Rad53 checkpoint kinase.


Add a reference

Inventor Information

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