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Anti-L1CAM [S10-33]

Info

Applications ELISA IF
Antigen/Gene or Protein Targets L1 adhesion molecule
Reactivity Mouse
Relevance L1 adhesion molecule (L1CAM) is an axonal glycoprotein belonging to the immunoglobulin supergene family. It is a transmembrane protein and a cell adhesion molecule with an important role in the development of the nervous system, including neuronal migration, and differentiation. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus).
Host Rat
Myeloma Used Sp2/0
Research Area Adhesion, Cell Signaling & Signal Transduction, Neurobiology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Maddaluno et al. 2009. J Exp Med. 206(3):623-35. PMID: 19273627.

The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells.

Europe PMC ID: 19273627


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References: 2 entries

Maddaluno et al. 2009. J Exp Med. 206(3):623-35. PMID: 19273627.

The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells.


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Inventor Information

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