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Anti-BAIP2 [CA-A10-2]

Invented at IFOM-IEO

Info

Applications IF WB
Antigen/Gene or Protein Targets Brain speciļ¬c angiogenesis inhibitor 1 associated protein 2
Reactivity Human and Mouse
Relevance Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
Host Mouse
Myeloma Used Sp2/0
Research Area Cell Type or Organelle Marker, Neurobiology, Protein Degradation

References

There are 2 reference entries for this reagent.

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References: 2 entries

Disanza et al. 2006. Nat Cell Biol. 8(12):1337-47. PMID: 17115031.

Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex.

Europe PMC ID: 17115031


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References: 2 entries

Disanza et al. 2006. Nat Cell Biol. 8(12):1337-47. PMID: 17115031.

Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex.


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