Anti-RNTRE [15-B]
Invented at IFOM-IEO
- Datasheet
- References (2)
- Inventor Info
Info
Applications | IF IP WB |
Antigen/Gene or Protein Targets | RNTRE |
Synonyms | USP6NL |
Reactivity | Human |
Relevance | Related to the N terminus of tre oncogene (RNTRE, USP6NL) acts as a GTPase-activating protein for RAB5A and RAB43. RNTRE is involved in the receptor trafficking and the retrograde transport from the endocytic pathway to the Golgi apparatus. RNTRE is required for structural integrity of the Golgi complex. When in complex with EPS8, RNTRE inhibits internalization of EGFR. |
Host | Mouse |
Myeloma Used | Sp2/0 |
Research Area | Cell Signaling & Signal Transduction |
References: 2 entries
Lanzetti et al. 2004. Nature. 429(6989):309-14. PMID: 15152255.
Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.
Europe PMC ID: 15152255
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References: 2 entries
Lanzetti et al. 2004. Nature. 429(6989):309-14. PMID: 15152255.
Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.
Add a reference