Anti-RABX5 [G32-11]
Invented at IFOM-IEO
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | IP WB |
| Antigen/Gene or Protein Targets | RAB guanine nucleotide exchange factor (GEF) 1 |
| Synonyms | RAB guanine nucleotide exchange factor (GEF) 1, Rab5 GDP/GTP exchange factor, Rab5ef, Rabaptin 5 associated exchange factor for Rab5, Rabaptin-5-associated exchange factor for Rab5, Rabex 5, Rabex-5, RABGEF 1, Rabgef1 |
| Reactivity | Human and Mouse |
| Relevance | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Host | Mouse |
| Subclass | IgG2a kappa |
| Myeloma Used | Sp2/0 |
| Research Area | Cellular Transport |
References: 2 entries
Penengo et al. 2006. Cell. 124(6):1183-95. PMID: 16499958.
Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.
Europe PMC ID: 16499958
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References: 2 entries
Penengo et al. 2006. Cell. 124(6):1183-95. PMID: 16499958.
Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.
Add a reference
