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Anti-RABX5 [G32-11]

Info

Applications IP WB
Antigen/Gene or Protein Targets RAB guanine nucleotide exchange factor (GEF) 1
Synonyms RAB guanine nucleotide exchange factor (GEF) 1, Rab5 GDP/GTP exchange factor, Rab5ef, Rabaptin 5 associated exchange factor for Rab5, Rabaptin-5-associated exchange factor for Rab5, Rabex 5, Rabex-5, RABGEF 1, Rabgef1
Reactivity Human and Mouse
Relevance Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
Host Mouse
Subclass IgG2a kappa
Myeloma Used Sp2/0
Research Area Cellular Transport

References

There are 2 reference entries for this reagent.

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References: 2 entries

Penengo et al. 2006. Cell. 124(6):1183-95. PMID: 16499958.

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.

Europe PMC ID: 16499958


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References: 2 entries

Penengo et al. 2006. Cell. 124(6):1183-95. PMID: 16499958.

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.


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Inventor Information

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