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Anti-NUMA1 [AD6-1]

Info

Applications IF
Antigen/Gene or Protein Targets Nuclear Mitotic Apparatus Protein 1
Synonyms NMP 22, Nuclear matrix protein 22, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, NUMA 1, NUMA, NuMA protein, NUMA1, NUMA1_HUMAN, SP H antigen, SP-H antigen, Structural nuclear protein
Reactivity Human
Relevance Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles during symmetric cell divisions, functioning as a tether linking bulk microtubules of the spindle to centrosomes.
Host Mouse
Myeloma Used Sp2/0
Research Area Cell Cycle

References

There are 4 reference entries for this reagent.

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References: 4 entries

Carminati et al. 2016. Nat Struct Mol Biol. 23(2):155-63. PMID: 26751642.

Gallini et al. 2016. Curr Biol. 26(4):458-69. PMID: 26832443.

NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation.

Europe PMC ID: 26832443

Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation.

Europe PMC ID: 26751642


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References: 4 entries

Carminati et al. 2016. Nat Struct Mol Biol. 23(2):155-63. PMID: 26751642.

Gallini et al. 2016. Curr Biol. 26(4):458-69. PMID: 26832443.

NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation.

Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation.


Add a reference

Inventor Information

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