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Anti-Eps15 [15-3T]

Info

Applications IF IP WB
Antigen/Gene or Protein Targets Epidermal growth factor receptor pathway substrate 15
Synonyms AF 1P, AF 1p protein, AF1P, ALL1 fused gene from chromosome 1, Epidermal growth factor receptor pathway substrate 15, Epidermal growth factor receptor substrate 15, EPS 15, MLLT 5, MLLT5
Reactivity Human and Mouse
Relevance The eps15 protein (EGFR pathway substrate clone 15) is tyrosine phosphorylated by the activation of the EGF and PDGF receptors. It was first identified as an 896 amino acid protein in mouse. Subsequent cloning of the human protein showed 90% homology to the mouse form. Several physiological functions have been proposed for eps15. Phosphorylation by EGF and PDGF receptors indicates that eps15 plays a role in signal transduction, cell proliferation and endocytosis.
Host Mouse
Myeloma Used Sp2/0
Research Area Cell Signaling & Signal Transduction

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