Anti-Eps15 [15-3T]
Invented at IFOM-IEO
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Info
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Epidermal growth factor receptor pathway substrate 15 |
| Synonyms | AF 1P, AF 1p protein, AF1P, ALL1 fused gene from chromosome 1, Epidermal growth factor receptor pathway substrate 15, Epidermal growth factor receptor substrate 15, EPS 15, MLLT 5, MLLT5 |
| Reactivity | Human and Mouse |
| Relevance | The eps15 protein (EGFR pathway substrate clone 15) is tyrosine phosphorylated by the activation of the EGF and PDGF receptors. It was first identified as an 896 amino acid protein in mouse. Subsequent cloning of the human protein showed 90% homology to the mouse form. Several physiological functions have been proposed for eps15. Phosphorylation by EGF and PDGF receptors indicates that eps15 plays a role in signal transduction, cell proliferation and endocytosis. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cell Signaling & Signal Transduction |
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