Anti-DLG1 [B7-1]
Invented at IFOM-IEO
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Info
| Applications | IF |
| Antigen/Gene or Protein Targets | Discs Large Homolog 1 |
| Synonyms | Discs large homolog 1, discs large, Drosophila, homolog of, 1, discs, large homolog 1 (Drosophila), Disks large homolog 1, dJ1061C18.1.1, DKFZp761P0818, DKFZp781B0426, DLG 1, DLG1, DLG1_HUMAN, DLGH 1, DLGH1, hDlg, Presynaptic protein SAP97, SAP 97 |
| Reactivity | Human |
| Relevance | Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Neurobiology, Virology |
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