Anti-CD73 [CI59-B1-3]
Invented at IFOM-IEO
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Info
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Ecto 5' nucleotidase |
| Synonyms | 5'-Nucleotidase Ecto; 5-NT; NT5; NTE; Purine 5-Prime-Nucleotidase; 5 Nucleotidase (CD73); CD73 Antigen; CALJA; CD73; E5NT; ENT; NT; EN |
| Reactivity | Human |
| Relevance | CD73, also known as Ecto-5'-nucleotidase, catalyzes the conversion of purine 5' mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cardiovascular, Cell Type or Organelle Marker, Immunology, Stem Cell Biology |
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