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Anti-IL22 [L8P2F10*A3]

Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited

Info

Catalogue Number 152863
Applications ELISA FACS WB
Antigen/Gene or Protein Targets Interleukin 22 (IL22)
Synonyms Cytokine Zcyto18, IL 10 related T cell derived inducible factor, IL 21, IL 22, IL D110, IL TIF, IL-10-related T-cell-derived-inducible factor, IL-22, IL-TIF, IL21, Il22, ILD110, ILTIF
Reactivity Salmon and Rainbow Trout
Relevance Monoclonal antibody which detects IL-22 in Salmon and Rainbow trout.

Background and Research Application
IL-22 is an α-helical cytokine that binds to a heterodimeric cell surface receptor composed of IL-10R2 and IL-22R1 subunits. IL-22R is expressed on tissue cells, and it is absent on immune cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide sequence located near the C-terminus
Immunogen UniProt ID C5VUR1
Positive Control WB - recombinant IL22 (rIL22), gill lysates, FACS - isolated leukocytes, kidney and spleen cells
Subclass IgG1 kappa
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Production Details
Purified using multi-step affinity chromatography with protein A.

Storage Conditions
Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles.

Concentration
1mg/ml as standard
Research Area Aquaculture

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