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Anti-IFN-γ [N2P2D5*A10]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152858
Applications ELISA FACS WB
Antigen/Gene or Protein Targets Interferon-gamma (IFNγ)
Synonyms IFG, IFI, IFN gamma, IFN, immune, IFN-gamma, IFNG, IFNG_HUMAN, Immune interferon, Interferon gamma
Reactivity Salmon and Rainbow Trout
Relevance Monoclonal antibody to detect IFNγ in fish models.

Background and Research Application
The zebrafish genome contains ten genes that encode class II cytokine-like peptides, of which the two that are related most closely to mammalian interferon gamma (IFN-gamma) were named IFN-γ1and IFN-γ2. IFNγ, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFNγ is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression.
Host Mouse
Immunogen Peptide sequence - see figure
Immunogen UniProt ID Q5QRA1
Positive Control WB - recombinant IFNγ and kidney lysates, FACS - isolated leukocytes, kidney and spleen cells
Subclass Not Known
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Production Details
Purified using multi-step affinity chromatography with protein A.

Storage Conditions
Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles.

Concentration
1mg/ml as standard
Research Area Aquaculture

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