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Monoclonal Antibodies

Anti-Von Willebrand Factor [F8/86]

Invented by Dr Jacqueline Cordell from University of Oxford
Invented at University of Oxford
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Info

Catalogue Number 152836
Applications IHC WB
Antigen/Gene or Protein Targets Factor VIII-related antigen (Von Willebrand factor / vWf)
Reactivity Human
Relevance Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD).
Host Mouse
Immunogen Von Willebrand factor isolated from human plasma
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT. Ultroser G (**) can be used at 1% if the cells are not growing well.
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Cardiovascular, Stem Cell Biology

References

There are 6 reference entries for this reagent.

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References: 6 entries

Ellis et al. 2012. J Oncol. 2012:651507. PMID: 22545050.

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Angiogenesis in Paget's Disease of the Vulva and the Breast: Correlation with Microvessel Density.

Europe PMC ID: 22545050

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Hussein et al. 2009. Leukemia. 23(5):852-5. PMID: 19194467.

IHC

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MPLW515L mutation in acute megakaryoblastic leukaemia.

Europe PMC ID: 19194467

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Disse et al. 2009. Blood. 113(4):973-80. PMID: 18945966.

IHC

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Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.

Europe PMC ID: 18945966

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Add a reference

References: 6 entries

Ellis et al. 2012. J Oncol. 2012:651507. PMID: 22545050.

View  

Angiogenesis in Paget's Disease of the Vulva and the Breast: Correlation with Microvessel Density.

View  

Hussein et al. 2009. Leukemia. 23(5):852-5. PMID: 19194467.

IHC

View  

MPLW515L mutation in acute megakaryoblastic leukaemia.

View  

Disse et al. 2009. Blood. 113(4):973-80. PMID: 18945966.

IHC

View  

Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.

View  

Add a reference

Inventor Information