Anti-SARS Nucleocaspid [1C7C7]
Invented at Icahn School Of Medicine At Mount Sinai
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Info
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | SARS nucleoprotein (NP) |
| Synonyms | Nucleoprotein, Protein N, SARS coronavirus N protein, SARS CoV |
| Reactivity | Virus |
| Relevance | Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions. |
| Host | Mouse |
| Subclass | IgG2a |
| Research Area | Virology |
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