Anti-NPC1 [17B5]
Invented at Icahn School Of Medicine At Mount Sinai
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Info
| Applications | WB |
| Antigen/Gene or Protein Targets | NPC1 |
| Synonyms | Niemann Pick C1 protein precursor, Niemann Pick disease, type C1, Niemann-Pick C1 protein |
| Reactivity | Human |
| Relevance | Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals. |
| Host | Mouse |
| Subclass | IgG1 |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism, Neurobiology |
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