Anti-GluR2,4 [3A11]
Invented at Icahn School Of Medicine At Mount Sinai
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | GluR2 & GluR4 |
| Synonyms | AMPA 2, AMPA selective glutamate receptor 2, AMPA-selective glutamate receptor 2, AMPA2, GluA2, GLUR 2, GLUR B, GluR K2, GluR-2, GluR-B, GluR-K2, GLUR2, GLURB, Glutamate receptor 2, Glutamate receptor ionotropic AMPA 2, Glutamate receptor ionotropic, Gria2 |
| Reactivity | Human, Primate and Rat |
| Relevance | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Host | Mouse |
| Subclass | IgG2a |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Metabolism |
References: 2 entries
Siegel et al. 1995. J Neurosci. 15(4):2707-19. PMID: 7722624.
Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1.
Europe PMC ID: 7722624
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References: 2 entries
Siegel et al. 1995. J Neurosci. 15(4):2707-19. PMID: 7722624.
Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1.
Add a reference
