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Anti-GluR2,4 [3A11]

Info

Applications ELISA IHC WB
Antigen/Gene or Protein Targets GluR2 & GluR4
Synonyms AMPA 2, AMPA selective glutamate receptor 2, AMPA-selective glutamate receptor 2, AMPA2, GluA2, GLUR 2, GLUR B, GluR K2, GluR-2, GluR-B, GluR-K2, GLUR2, GLURB, Glutamate receptor 2, Glutamate receptor ionotropic AMPA 2, Glutamate receptor ionotropic, Gria2
Reactivity Human, Primate and Rat
Relevance Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Host Mouse
Subclass IgG2a
Research Area Cancer, Cell Signaling & Signal Transduction, Metabolism

References: 1 entry

Siegel et al. 1995. J Neurosci. 15(4):2707-19. PMID: 7722624.


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References: 1 entry

Siegel et al. 1995. J Neurosci. 15(4):2707-19. PMID: 7722624.


Add a reference

References: 1 entry

Siegel et al. 1995. J Neurosci. 15(4):2707-19. PMID: 7722624.


Add a reference


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