Anti-Listeria monocytogenes antigen 2 [2:4 E10]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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![ELISA detection showing the sensitivity and specificity of anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/64b078fa-1fca-418a-afb1-3a1385e5e7b4.jpg)
![ELISA detection showing the sensitivity and specificity of anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/4b4c837f-a161-49c7-8aba-3d466f2ed25c.jpg)
![ELISA detection showing the sensitivity and specificity of anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/64b078fa-1fca-418a-afb1-3a1385e5e7b4.jpg)
![ELISA detection showing the sensitivity and specificity of anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/4b4c837f-a161-49c7-8aba-3d466f2ed25c.jpg)
![Image thumbnail for Anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/64b078fa-1fca-418a-afb1-3a1385e5e7b4.jpg)
![Image thumbnail for Anti-Listeria monocytogenes antigen 2 [2:4 E10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/4b4c837f-a161-49c7-8aba-3d466f2ed25c.jpg)
| Catalogue Number | 152798 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Listeria monocytogenes antigen 2 protein |
| Synonyms | Listeria monocytogenes |
| Reactivity | L. monocytogenes |
| Relevance |
Monoclonal antibody which detects Listeria monocytogenes antigen 2 protein. Background and Research Application The genus Listeria comprises six species: L. monocytogenes, L. innocua, L. welshimeri, L. seeligeri, L. ivanovii and L. grayi. Listeria monocytogenes, the most commonly isolated pathogenic member, is associated with a wide spectrum of human and animal diseases. In the smear from the original tissue, L. monocytogenes may appear as gram-positive coccobacilli that may be confused with Streptococcus agalactiae (group B), enterococci, or Corynebacterium spp. Listeria is differentiated from streptococci by a positive catalase test. L. monocytogenes is the only species of the genus Listeria that has been clearly documented as a pathogen for humans. The forms of disease caused by this organism are myriad and age-related. The most common clinical manifestations are meningitis and septicaemia. Listeria monocytogenes, a food-borne intracellular animal and human pathogen, interacts with infected host cells both prior to entry and during the intracellular phase of infection. |
| Host | Mouse |
| Immunogen | Listeria monocytogenes antigen 2 protein |
| Positive Control | Whole cell lysates of L. monocytogenes |
| Subclass | IgG2b kappa |
| Molecular Weight (kDa) | 74, 67, (faint 72) |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Notes |
Production Details Purified using multi-step affinity chromatography with protein A. Storage Conditions Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles. Points of Interest Specific for Listeria monocytogenes, not reactive for S. aureus, S. faecalis, B. subtilis, E. coli - Whole heat-killed liesteria cells were used at the immunogen for the genertion of these antibodies - Both mAbs [2:4 E10] and [2:13 C5] detect the same antigen but has different Ig subclass. Concentration 1mg/ml as standard |
| Research Area | Bacteriology |
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