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Anti-DRAM2 [VAB24-P1C8*A3]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152793
Applications ELISA IHC WB
Antigen/Gene or Protein Targets DNA-Damage Regulated Autophagy Modulator 2 (DRAM2)
Synonyms 2010305N14Rik, 2610318G18Rik, AI647667, damage regulated autophagy modulator 2, DNA damage regulated autophagy modulator 2, DNA damage regulated autophagy modulator protein 2, DNA damage-regulated autophagy modulator protein 2, Dram2, DRAM2_HUMAN, PRO180, PSEC0031, RP5-1180E21.1, Tmem77, Transmembrane protein 77, WWFQ154
Reactivity Human
Relevance DRAM2's expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide HGLTLYDTAP. Note that peptide immunogen is identical in sheep (Ovis aries), cow (Bos taurus), dog (Canis familiaris), pig (Sus scrofa) and horse (Equus caballus).
Positive Control IHC - formalin-fixed, paraffin-embedded multi tumour tissue microarray
Subclass IgG1 kappa
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes For IHC antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
Research Area Apoptosis and Programmed Cell Death, Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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