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Anti-DRAM2 [VAB24-P1C8*A3]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152793
Applications ELISA IHC WB
Antigen/Gene or Protein Targets DNA-Damage Regulated Autophagy Modulator 2 (DRAM2)
Synonyms 2010305N14Rik, 2610318G18Rik, AI647667, damage regulated autophagy modulator 2, DNA damage regulated autophagy modulator 2, DNA damage regulated autophagy modulator protein 2, DNA damage-regulated autophagy modulator protein 2, Dram2, DRAM2_HUMAN, PRO180, PSEC0031, RP5-1180E21.1, Tmem77, Transmembrane protein 77, WWFQ154
Reactivity Human
Relevance DRAM2's expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide HGLTLYDTAP. Note that peptide immunogen is identical in sheep (Ovis aries), cow (Bos taurus), dog (Canis familiaris), pig (Sus scrofa) and horse (Equus caballus).
Subclass IgG1 kappa
Positive Control IHC - formalin-fixed, paraffin-embedded multi tumour tissue microarray
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes For IHC antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
Research Area Apoptosis and Programmed Cell Death, Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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