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Anti-activated MMP1 [5C10]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152766
Applications WB
Antigen/Gene or Protein Targets activated human matrix metalloproteinase 1 (MMP1)
Synonyms actMMP-1, actMMP1, activated-MMP1, activated MMP1, activated-MMP-1, activated MMP-1, Fibroblast collagenase
Reactivity Human
Relevance Matrix metalloproteinases (MMPs) are synthesized as inactive zymogens with a pro-peptide domain that must be removed before the enzyme is active. MMP1 breaks down the interstitial collagens, types I, II, and III hence it is an important feature of development, morphogenesis, tissue repair and remodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide; FVLTEGNPRC
Subclass IgG1 kappa
Positive Control Activated recombinant MMP-1
Molecular Weight (kDa) 40
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction

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