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Anti-Cytochrome P450 2J2 [Z9P1G9*A2]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152762
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Cytochrome P450, family 2, subfamily J, polypeptide 2 (CYP2J2)
Synonyms Arachidonic acid epoxygenase, CYPIIJ2
Reactivity Human
Relevance Cytochrome P450 2J2 metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. Localised to the endoplasmic reticulum membrane; microsome membrane.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide KFTFRPPNNE (C-terminal sequence)
Subclass IgG
Positive Control Pooled liver microsomes
Molecular Weight (kDa) 58
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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