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Anti-SPATA25 [Z37P3H11*B2]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152757
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Spermatogenesis Associated 25 (SPATA25)
Synonyms Testis-specific gene 23 protein
Reactivity Human
Relevance SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception.
Host Mouse
Immunogen Peptide Sequence – LVRSKRGQP
Positive Control Jurkat cell lysate
Subclass IgG
Molecular Weight (kDa) 23
Myeloma Used P3X63Ag8.653
Strain Balb/c
Research Area Developmental Biology

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