Cancer Research Technology
Log in Register
Menu

Anti-JMY [HMY117]

Invented by Helen Turley at University of Oxford

Info

Catalogue Number 152747
Applications IHC WB
Antigen/Gene or Protein Targets JMY
Reactivity Human
Relevance The anti-JMY [HMY117] antibody recognises uman JMY. JMY is a p300-binding protein with dual action: by enhancing P53 transcription in the nucleus, it plays an important role in the cellular response to DNA damage, while by promoting actin filament assembly in the cytoplasm; it induces cell motility in vitro. It might act either as tumor suppressor or as oncogene. This antibody may be used in research but also as a diagnostic tool.
Host Mouse
Immunogen Synthetic peptide from the c terminus of the peptide sequence, identical for both isoform 1 and 2
Positive Control MCF7, HeLa
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Research Area Apoptosis and Programmed Cell Death

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Adighibe et al. 2014. Virchows Arch. 465(6):715-22. PMID: 25280461.

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.

Europe PMC ID: 25280461


Add a reference

References: 2 entries

Adighibe et al. 2014. Virchows Arch. 465(6):715-22. PMID: 25280461.

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.


Add a reference