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Anti-Leu2, Recombinant [UCH-T4]

Invented by Prof Peter Beverley at Imperial College

Info

Catalogue Number 152731
Applications FACS IHC IF
Antigen/Gene or Protein Targets Leu2 (CD8)
Reactivity Human
Relevance Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. UCH-T4 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of T4/T8 ratios in immune deficiencies, rheumatoid arthritis, multiple sclerosis, etc.
Host Mouse
Immunogen Thymocytes followed by Sezary T cells.
Subclass IgG1
Research Area Immunology, Stem Cell Biology
Notes Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References: 2 entries

Original hybridoma first published in: Kee et al. 2000. J Cell Biochem. 78(1):97-111. PMID: 10797569.

beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.

Europe PMC ID: 10797569


Add a reference

References: 2 entries

Original hybridoma first published in: Kee et al. 2000. J Cell Biochem. 78(1):97-111. PMID: 10797569.

beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.

Europe PMC ID: 10797569


Add a reference

References: 2 entries

Original hybridoma first published in: Kee et al. 2000. J Cell Biochem. 78(1):97-111. PMID: 10797569.

beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.


Add a reference


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