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Anti-Leu1, Recombinant [UCH-T2]

Invented by Prof Peter Beverley at Imperial College

Info

Catalogue Number 152730
Applications IHC IF WB
Antigen/Gene or Protein Targets Leu1 (CD5)
Reactivity Human
Relevance Leu-1 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. Absence of the Leu-1 marker on childhood ALL cells is associated with a more favourable prognosis. UCH-T2 is useful for detection of T cells in peripheral blood and lymph nodes and categorisation of T cell lymphomas and B cell chronic lymphocytic leukaemia.
Host Mouse
Immunogen Thymocytes followed by Sezary T cells.
Subclass IgG2a
Research Area Immunology, Stem Cell Biology
Notes Recommended for Immunofluorescence and immunostaining of frozen samples and the enrichment of T cell populations by cell sorting or panning.

Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References: 1 entry

Original hybridoma first published in: Gary-Gouy et al. 2007. J Immunol. 179(7):4335-44. PMID: 17878328.


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References: 1 entry

Original hybridoma first published in: Gary-Gouy et al. 2007. J Immunol. 179(7):4335-44. PMID: 17878328.


Add a reference

References: 1 entry

Original hybridoma first published in: Gary-Gouy et al. 2007. J Immunol. 179(7):4335-44. PMID: 17878328.


Add a reference


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