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|Applications||IHC IF WB|
|Antigen/Gene or Protein Targets||Leu1 (CD5)|
|Relevance||Leu-1 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. Absence of the Leu-1 marker on childhood ALL cells is associated with a more favourable prognosis. UCH-T2 is useful for detection of T cells in peripheral blood and lymph nodes and categorisation of T cell lymphomas and B cell chronic lymphocytic leukaemia.|
|Immunogen||Thymocytes followed by Sezary T cells.|
|Research Area||Immunology, Stem Cell Biology|
Recommended for Immunofluorescence and immunostaining of frozen samples and the enrichment of T cell populations by cell sorting or panning.
Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.
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