Cancer Research Technology
Log in Register
Menu

Anti-DNA Ligase 1 [7A12]

Invented by Julian Gannon at The Francis Crick Institute

Info

Catalogue Number 152694
Applications ELISA IHC IP WB
Antigen/Gene or Protein Targets DNA Ligase 1
Reactivity Bovine and Human
Relevance DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.
Host Mouse
Immunogen Bovine DNA Ligase I
Subclass IgG1
Molecular Weight (kDa) 125
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References

There are 4 reference entries for this reagent.

View All References

References: 4 entries

Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.

WB

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.

Europe PMC ID: 18440984

Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.

Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.

Europe PMC ID: 8264597


Add a reference

References: 4 entries

Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.

WB

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.

Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.

Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.


Add a reference