Anti-CD13 [22A5]
Invented at Queen Mary University of London
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 152690 |
| Applications | FACS IHC IP |
| Antigen/Gene or Protein Targets | Aminopeptidase N (CD13) |
| Synonyms | Alanyl Aminopeptidase; Membrane; Microsomal Aminopeptidase; Aminopeptidase M; Myeloid Plasma Membrane Glycoprotein CD13; GP150; CD13; PEPN |
| Reactivity | Human |
| Relevance | Aminopeptidase N (CD13) is a cell-surface metalloprotease involved in the metabolism of regulatory peptides. 22A5 may be useful for the diagnosis and immunophenotyping of leukaemia. |
| Host | Mouse |
| Immunogen | A cell suspension containing osteoclasts from osteoclastomas. |
| Positive Control | Cells of myelomonocytic lineage |
| Subclass | IgG2a kappa |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Cell Type or Organelle Marker, Metabolism, Protein Degradation, Stem Cell Biology |
References: 10 entries
Murray et al. 1995. Leuk Lymphoma. 17(5-6):501-8. PMID: 7549844.
Immunocytochemical studies of an antigen in a human T-cell lymphoma line (Jurkat) recognized by certain monoclonal antibodies to CD-13 (aminopeptidase-N).
Europe PMC ID: 7549844
van Hal et al. 1994. J Immunol. 153(6):2718-28. PMID: 7915741.
Potential indirect anti-inflammatory effects of IL-4. Stimulation of human monocytes, macrophages, and endothelial cells by IL-4 increases aminopeptidase-N activity (CD13; EC 3.4.11.2).
Europe PMC ID: 7915741
Ashmun et al. 1990. Blood. 75(2):462-9. PMID: 1967220.
Metalloprotease activity of CD13/aminopeptidase N on the surface of human myeloid cells.
Europe PMC ID: 1967220
Look et al. 1989. J Clin Invest. 83(4):1299-307. PMID: 2564851.
FACS
Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.
Europe PMC ID: 2564851
Horton et al. 1985. Cancer Res. 45(11 Pt 2):5663-9. PMID: 4053038.
Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens.
Europe PMC ID: 4053038
Add a reference
References: 10 entries
Murray et al. 1995. Leuk Lymphoma. 17(5-6):501-8. PMID: 7549844.
Immunocytochemical studies of an antigen in a human T-cell lymphoma line (Jurkat) recognized by certain monoclonal antibodies to CD-13 (aminopeptidase-N).
van Hal et al. 1994. J Immunol. 153(6):2718-28. PMID: 7915741.
Potential indirect anti-inflammatory effects of IL-4. Stimulation of human monocytes, macrophages, and endothelial cells by IL-4 increases aminopeptidase-N activity (CD13; EC 3.4.11.2).
Ashmun et al. 1990. Blood. 75(2):462-9. PMID: 1967220.
Metalloprotease activity of CD13/aminopeptidase N on the surface of human myeloid cells.
Look et al. 1989. J Clin Invest. 83(4):1299-307. PMID: 2564851.
FACS
Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.
Horton et al. 1985. Cancer Res. 45(11 Pt 2):5663-9. PMID: 4053038.
Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens.
Add a reference
