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Anti-PLAP [H17E2]

Invented by Prof Walter Bodmer at University of Oxford

Info

Catalogue Number 152689
Applications ELISA IHC
Antigen/Gene or Protein Targets Placenta-specific isozyme of Alkaline Phosphatase (PLAP)
Reactivity Human
Relevance Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. The detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer. HD 11F7 has potential uses in the diagnosis of ovarian and testicular tumours. The antibody detects both Regan and Nagao isoenzymes.
Host Mouse
Immunogen Placental membranes prepared from fresh term placenta
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker

References

There are 10 reference entries for this reagent.

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References: 10 entries

Multicolor flow cytometry and nanoparticle tracking analysis of extracellular vesicles in the plasma of normal pregnant and pre-eclamptic women.

Europe PMC ID: 24227753

Dragovic et al. 2013. Biol Reprod. 89(6):151. PMID: 24227753.

Tucker et al. 1985. Br J Cancer. 51(5):631-9. PMID: 2986664.

Epenetos et al. 1985. Br J Cancer. 51(5):641-4. PMID: 3994908.

Serum marker potential of placental alkaline phosphatase-like activity in testicular germ cell tumours evaluated by H17E2 monoclonal antibody assay.

Europe PMC ID: 2986664

Monoclonal antibody assay of serum placental alkaline phosphatase in the monitoring of testicular tumours.

Europe PMC ID: 3994908

Travers et al. 1984. Int J Cancer. 33(5):633-41. PMID: 6202646.

Preparation and characterization of monoclonal antibodies against placental alkaline phosphatase and other human trophoblast-associated determinants.

Europe PMC ID: 6202646

Epenetos et al. 1984. Br J Cancer. 49(1):11-5. PMID: 6362705.

An immunohistological study of testicular germ cell tumours using two different monoclonal antibodies against placental alkaline phosphatase.

Europe PMC ID: 6362705


Add a reference

References: 10 entries

Multicolor flow cytometry and nanoparticle tracking analysis of extracellular vesicles in the plasma of normal pregnant and pre-eclamptic women.

Dragovic et al. 2013. Biol Reprod. 89(6):151. PMID: 24227753.

Tucker et al. 1985. Br J Cancer. 51(5):631-9. PMID: 2986664.

Epenetos et al. 1985. Br J Cancer. 51(5):641-4. PMID: 3994908.

Serum marker potential of placental alkaline phosphatase-like activity in testicular germ cell tumours evaluated by H17E2 monoclonal antibody assay.

Monoclonal antibody assay of serum placental alkaline phosphatase in the monitoring of testicular tumours.

Travers et al. 1984. Int J Cancer. 33(5):633-41. PMID: 6202646.

Preparation and characterization of monoclonal antibodies against placental alkaline phosphatase and other human trophoblast-associated determinants.

Epenetos et al. 1984. Br J Cancer. 49(1):11-5. PMID: 6362705.

An immunohistological study of testicular germ cell tumours using two different monoclonal antibodies against placental alkaline phosphatase.


Add a reference