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Anti-hnRNP-K (isoform1) [N10 P2D3*G2]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 152670
Applications IHC WB
Antigen/Gene or Protein Targets Heterogeneous nuclear ribonucleoprotein K – isoform 1, hnRNP-K, hnRNPK
Reactivity Human
Relevance The heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a nucleic acid-binding protein that serves as a docking platform integrating transduction pathways to nucleic acid-directed processes. This protein has recently emerged as an important player in carcinogenesis process. HnRNP K is overexpressed in several human cancers and its aberrant cytoplasmic localization has been associated with a worse prognosis for patients, suggesting that it has a role in cancer progression.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide SVKQYSGKFF (C-terminal sequence)
Positive Control IHC - formalin-fixed, paraffin-embedded colorectal cancer sections; WB - Jurkat cell lysate
Subclass IgG1 kappa
Strain Balb/c
Notes Immunogen peptide sequence is common to mouse, rat, rabbit, chicken, sheep, dog, pig, horse.
Research Area Cell Cycle, Epigenetics & Nuclear Signalling

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