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Anti-NS5B [1A4]

Info

Catalogue Number 152664
Applications IF WB
Antigen/Gene or Protein Targets Hepatitis C virus non-structural protein 5B
Reactivity Virus
Relevance Hepatitis C virus (HCV) encodes a polyprotein that is cleaved into at least 10 viral proteins namely E1, E2, core, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. Non-structural 5B protein (NS5B) is HCV’s RNA dependant RNA polymerase and is critical for viral replication.
Host Mouse
Immunogen GST-NS5B (residues 1-346) fusion protein of a HCV genotype 2a strain
Subclass IgG2a
Myeloma Used Sp2/0-Ag14
Research Area Virology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Aweya et al. 2015. Virology. 474:41-51. PMID: 25463603.

NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release.

Europe PMC ID: 25463603


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References: 2 entries

Aweya et al. 2015. Virology. 474:41-51. PMID: 25463603.

NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release.


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Inventor Information

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