Anti-M1 [1G1A12]
Invented at A*STAR Accelerate Technologies Pte Ltd
- Datasheet
- References (2)
- Inventor Info
Info
![Western blotting (A) or ELISA (B) on a lysate prepared from MDCK cells either mock infected or infected with different strains of influenza A virus using anti-M1 [1G1A12].](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/1809e712-f0f8-47ea-abf1-aeeb3972d78e.png)
![Immunofluorescence on cos-7 cells transfected with a plasmid containing the M1 open reading frame using anti-M1 [1G1A12], Cells
were fixed with 4% paraformaldehyde, permeabilized with 0.1% Triton X-100 and stained with anti-M1 [1G1A12] followed by FITC-conjugated secondary goat anti-mouse. DAPI counterstain is shown in blue (left panel) and antibody staining in green (middle panel).](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/3482cc00-07db-4c81-aedc-7449c89ccf5a.png)
![Western blotting (A) or ELISA (B) on a lysate prepared from MDCK cells either mock infected or infected with different strains of influenza A virus using anti-M1 [1G1A12].](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/1809e712-f0f8-47ea-abf1-aeeb3972d78e.png)
![Immunofluorescence on cos-7 cells transfected with a plasmid containing the M1 open reading frame using anti-M1 [1G1A12], Cells
were fixed with 4% paraformaldehyde, permeabilized with 0.1% Triton X-100 and stained with anti-M1 [1G1A12] followed by FITC-conjugated secondary goat anti-mouse. DAPI counterstain is shown in blue (left panel) and antibody staining in green (middle panel).](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/3482cc00-07db-4c81-aedc-7449c89ccf5a.png)
![Image thumbnail for Anti-M1 [1G1A12]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/1809e712-f0f8-47ea-abf1-aeeb3972d78e.png)
![Image thumbnail for Anti-M1 [1G1A12]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/3482cc00-07db-4c81-aedc-7449c89ccf5a.png)
![Image thumbnail for Anti-M1 [1G1A12]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/4f06d23a-4a15-4fe5-b0ad-27bdb0e69717.png)
| Catalogue Number | 152662 |
| Applications | ELISA IF Fn WB |
| Antigen/Gene or Protein Targets | Influenza A virus matrix 1 protein |
| Reactivity | Virus |
| Relevance | The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding. |
| Host | Mouse |
| Immunogen | GST-M1 fusion protein |
| Positive Control | Transfected COS-7 cells |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Research Area | Virology |
References: 2 entries
Barnwal et al. 2015. Antiviral Res. 116:55-61. PMID: 25666762.
Fn
A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication.
Europe PMC ID: 25666762
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References: 2 entries
Barnwal et al. 2015. Antiviral Res. 116:55-61. PMID: 25666762.
Fn
A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication.
Add a reference
