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Anti-SGT [6A4]

Info

Catalogue Number 152653
Applications IF WB
Antigen/Gene or Protein Targets Small glutamine-rich TPR-repeat containing protein
Reactivity Virus
Relevance The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated.
Host Mouse
Immunogen GST-SGT fusion protein
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Research Area Apoptosis and Programmed Cell Death, Cell Cycle, Cell Signaling & Signal Transduction, Virology

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