Anti-SGT [6A4]
Invented at A*STAR Accelerate Technologies Pte Ltd
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Info
Catalogue Number | 152653 |
Applications | IF WB |
Antigen/Gene or Protein Targets | Small glutamine-rich TPR-repeat containing protein |
Reactivity | Virus |
Relevance | The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated. |
Host | Mouse |
Immunogen | GST-SGT fusion protein |
Subclass | IgG1 |
Myeloma Used | Sp2/0-Ag14 |
Research Area | Apoptosis and Programmed Cell Death, Cell Cycle, Cell Signaling & Signal Transduction, Virology |
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