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Anti-SΔ3 [7G12]

Info

Catalogue Number 152651
Applications IP WB
Antigen/Gene or Protein Targets S protein of the SARS coronavirus
Reactivity Virus
Relevance Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The S protein, which forms morphologically characteristic projections on the virion surface, is responsible for binding to cellular receptor and mediating the fusion between viral and cellular membranes. The SΔ3 is a fragment containing residues from 168 to 461 of the S protein.
Host Mouse
Immunogen GST-SΔ3 fusion protein
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Notes This antibody was found to have no viral neutralizing activity (Lip et al., 2006).
Research Area Virology

References: 2 entries

Lip et al. 2006. J Virol. 80(2):941-50. PMID: 16378996.

Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.

Europe PMC ID: 16378996


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References: 2 entries

Lip et al. 2006. J Virol. 80(2):941-50. PMID: 16378996.

Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.

Europe PMC ID: 16378996


Add a reference

References: 2 entries

Lip et al. 2006. J Virol. 80(2):941-50. PMID: 16378996.

Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.


Add a reference


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