Anti-SARS Nucleocaspid [6H3]
Invented at A*STAR Accelerate Technologies Pte Ltd
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![Immunofluorescence of VeroE6 cells over-expressing SARS-CoV N protein and labelled with anti-SARS Nucleocaspid [6H3].](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/4eb89f6c-09d7-4937-9da6-fe77c619156c.png)
![Western blotting on lysates prepared from SARS-CoV infected Vero E6 cells harvested at different timepoints post infection (T = 0, 8, 16 and 24 h) using anti-SARS Nucleocaspid [6H3].](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/36f0fa56-6c6f-449c-b08a-dc9fe344e3e8.png)
![Immunofluorescence of VeroE6 cells over-expressing SARS-CoV N protein and labelled with anti-SARS Nucleocaspid [6H3].](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/4eb89f6c-09d7-4937-9da6-fe77c619156c.png)
![Western blotting on lysates prepared from SARS-CoV infected Vero E6 cells harvested at different timepoints post infection (T = 0, 8, 16 and 24 h) using anti-SARS Nucleocaspid [6H3].](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/36f0fa56-6c6f-449c-b08a-dc9fe344e3e8.png)
![Image thumbnail for Anti-SARS Nucleocaspid [6H3]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/4eb89f6c-09d7-4937-9da6-fe77c619156c.png)
![Image thumbnail for Anti-SARS Nucleocaspid [6H3]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/36f0fa56-6c6f-449c-b08a-dc9fe344e3e8.png)
| Catalogue Number | 152645 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | SARS coronavirus nucleocapsid protein |
| Synonyms | Nucleoprotein, Protein N, SARS coronavirus N protein, SARS CoV |
| Reactivity | Virus |
| Relevance | Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions. |
| Host | Mouse |
| Immunogen | GST-N (residues 121-422) |
| Positive Control | SARS-CoV infected Vero E6 cells |
| Subclass | Inconclusive |
| Subclass Notes | Both Isotype assays negative |
| Myeloma Used | Sp2/0-Ag14 |
| Research Area | Virology |
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